BZ-9000 SERIES

Haze Reduction Function

Similar to deconvolution, this function eliminates fluorescent blurring, enabling visualization of weak fluorescent signals with sharp contrast and clarity

Quickly eliminates an out-of-focus image (fluorescence blurring) on the objective lens, greatly improving contrast and clarity.The “Real-Time Haze Reduction” function for quickly eliminating fluorescence blurring is also provided on the preview screen.

Raw image Haze reduction image
Mouse embryo (before implantation) (Courtesy of Mr. Atsushi Sawada, Laboratory for Embryonic Induction, RIKEN Center for Developmental Biology)
The blurring can be eliminated immediately
This image was taken using a conventional
fluorescence microscope.
The target fluorescence signals cannot be
recognized clearly due to fluorescence blurring.
The haze reduction function removes the light diffused on the unfocused surface (blurring). This allows accurate recognition of the location of the fluorescence signals.

HAZE REDUCTION IMAGE SAMPLES

Raw imageBacteria

Bacteria

Raw imageColon cancer cell (HT29)

Colon cancer cell (HT29)

ACTUAL ACHIEVEMENTS

Actual achievements obtained by using the BZ Series haze reduction function were introduced in the American scientific journal, Nature Immunology.

Title:
Mechanistic basis of pre-T cell receptor-mediated autonomous signaling critical for thymocyte development.
Researcher:
Dr. Sho Yamasaki, Laboratory for Cell Signaling, RIKEN Research Center for Allergy and Immunology, Yokohama, Japan
Reference Journal:
Nature Immunology, Volume 7 Number 1 January 2006 P 74, "BZ-8000 (KEYENCE) was used for deconvoluted fluorescence imaging."
Raw image   Haze reduction image
Intracellular location of GFP-labeled pre-T cell receptor
View Keyence on YouTube